Extraction of the Active Pharmacological Ingredients from Ibuprofen, Tetracycline, Naproxen and Ketofane Drugs
Keywords:
Ibuprofen, Tetracycline, Naproxen, Ketofane, DrugsAbstract
This study aimed to determine the extraction of active pharmaceutical ingredients from ibuprofen, tetracycline, naproxen and Ketofane. These experiments were conducted in the laboratories of the International University of Cyrene The concept of drug recycling is demonstrated by recovering active pharmaceutical ingredients from unused tablets and capsules. The process included liquid-solid extraction, filtration, and crystallization. The active pharmaceutical ingredients were up to standard. In the experiment a mortar and pestle was used to crush 3 tablet of Naproxen , Ibuprofen , Tetracycline , Ketofane the used 35ml of Acetone , Ethyl-acetate , Diethyl-ether and 10ml of distilled water (1:1) as solvent , stirrer to enhance solubility and separatory funnel for extraction process then dried at room temperature 25℃ for 7-10 days . melting point or solubility apparatus was used to confirm identification of the pure sample of Naproxen , Ibuprofen , Tetracycline , Ketofane and Acetone , Ethyl-acetate , Diethyl-ether titration to determine Separation of the active substance of it . The results presented showed a formed crystal of pure Naproxen , Ibuprofen , Tetracycline , Ketofane after 7-10 days , for purity identification separation apparatus was used . in the last measurement viewed change in drug solution values Ibuprofen (85%,70%,75%) , Tetracycline (51%,36%,49%), Naproxen (no-pain)( 80%,65%,70%) , Ketofane( 79% ,64%,69%) where use as solvents Acetone , Ethyl-acetate , Diethyl-ether .
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