The extent of the relationship between analgesics and kidney failure at Kidney Services Center Benghazi and Benghazi Medical Center

Abstract

Non-steroidal anti-inflammatory drug (NSAID) consumption has been associated to a higher risk of kidney problems. After NSAID administration, short-term use has been shown to resolve renal side effects. Aim: To investigate the impact of long-term NSAID use on kidney function and its association with the onset and progression of kidney failure, with a focus on the mechanisms underlying kidney injury and potential risk factors. Methods: Its analytical cross-sectional study was conducted to assess and patients in Benghazi Libya, was done by using constructive form questionnaire based on previous studies. Results: This cross-sectional study was aimed to assess the related between factor of random consumption of NSAID and kidney failure among patients in different Benghazi-hospitals . First in results were sociodemographic factors. As seen below all the participants in the study consider different ages 34.3.% of them their age range between (46-60) ,28.7. % range (31-45) ,23.3 % over 60 , 12.7% range ( 31-45)and only 1. % were under 1878.3% They had kidney failure, while 21.7% not They found that they did not suffer from kidney failure found that people with kidney failure had a family history of(.32.7%) while (69.3% ). They have no family history It was found that the percentage of people who take NSAIDs on a monthly (37.3%) , (22.7%) Weekly, (3.3%) Daily, (28.7%) Rarely and (8%) They never take it .(7%) of patients had Swelling in the feet or ankles after take NSAID ,(2.3%) decreased urination,(4.3%) General fatigue and (86.3%) hadn't any Symptoms. Patients were asked whether health centers provide sufficient information about NSAID. and it was found that(71.7%) said no and (28.3%) Obtain information. whether doctor advised to reduce or stop using NSAIDs due to kidney concerns (83%) said no and (17%). Conclusion: we conclude, while NSAIDs are effective in managing pain and inflammation, their potential to cause kidney failure, particularly with long-term use, must be recognized and addressed through informed patient education and proactive healthcare management.