Antibiotic Susceptibility Patterns of Gram Positive Bacteria (Streptococcus viridans and Enterococcus faecalis) Isolated Clinically from Patients in El Jalaa Hospital for Surgery and Accidents in Benghazi City – Libya

Abstract

Background: Streptococcus viridans bacteria and Enterococcus faecalis bacteria are considered gram positive and caused several diseases and the most famous of them is like infectious endocarditis. Objectives: To evaluate antibiotic resistance trends in Streptococcus Viridans and Enterococcus faecalis over time. Materials and Methods: This cross-sectional study was conducted on a group of 100 (69 males, 31 females) suspected of having gram-positive bacteria & in the age range of 14 days to over 46 years old in Al-Jalaa Hospital for surgery & accidents (Benghazi) from January to March in 2022. Using standard isolation and identification procedures a total of 100 isolates were obtained from patients. The isolated samples are 60 urine samples,3 stool samples and 27 swab samples and 10 semen samples. The antibiotics were used during the study period for all specimens were the antibiotics that demonstrated in-vitro activity regularly against all culture organisms. Results: Our study shows that Streptococcus viridans may be resistant to Amoxicillin and Cefuroxime & more sensitive to Ciprofloxacin and Levofloxacin whereas Enterococcus faecalis are more resistant to Amoxicillin and Sulfamethoxazole & more sensitive to levofloxacin. Conclusions: Susceptibility rates for some relevant antibiotics declined for clinically isolated bacteria. This worrisome trend highlights the need to improve antimicrobial stewardship efforts to limit unnecessary antibiotic use and preserve empirical treatment options.